Reversing Heart Damage: The Peptide Breakthrough Cardiologists Need to Know

Reversing Heart Damage: The Peptide Breakthrough Cardiologists Need to Know

Reversing Heart Damage: The Peptide Breakthrough Cardiologists Need to Knowbrenden henry
Published on: 19/10/2024

Reversing Heart Damage: The Peptide Breakthrough Cardiologists Need to Know Imagine being told that your unborn baby has a heart defect so severe that it can result in it either dying in the womb or being born with a hole in its heart. If the hole is too large, the prognosis can be grim. Traditionally, the only way to repair such a defect would be with a surgery to physically sew the hole shut. But what if science discovered something new, a completely natural peptide that could prevent the need for a risky heart surgery or the baby dying in the womb? Normally, this would be considered almost physically impossible. The medical community has long accepted that the heart has very limited regeneration potential, except under some exceptional circumstances. But this is the reality of Emily's story, and how a small peptide she took while pregnant was able to completely heal the hole in her baby's heart and lead it to be born with a healthy heart and no longer require any surgery. These are the type of results we are getting with our molecular bioenhancement coaching programs, by the way. But before I get into that, I just want to cover the type of heart defect that her baby had. This is known as a ventricular septal defect. This occurs when there is a hole in the septum which separates the two lower chambers of the heart, known as the right ventricle and the left ventricle. So normally during the systole, which is the phase of your heartbeat, you have blood that gets pumped out of the left ventricle into the aorta, and how much blood gets pumped out is known as the left ventricular ejection fraction. However, with a hole in the septum, some of that blood gets forced into the right ventricle, which can cause a pansystolic heart murmur and enlarge the right ventricle over time, and it can also provide back pressure to the lungs, which results in pulmonary hypertension. And so this all results in a reduction of the left ventricular ejection fraction and overall poor heart function. But peptides, they have been shown to work through several mechanisms to actually repair the heart from this damage, and not just in babies who have a higher degree of pluripotent cells, this is actually something which has been shown also after ischemic insults, such as a heart attack. These peptides work by reducing oxidative stress specifically in heart tissues, which can limit further damage, and stimulating cellular repair mechanisms, leading to the regeneration of damaged myocardial cells. They also enhance cardiac function after ischemic events by improving blood flow and oxygen supply to the heart muscle. I will cover the specific benefits and detailed mechanisms of how these peptides work after sharing Emily's story. In a small village in Russia, there lived a woman named Emily. She was known for her unwavering resilience and kind heart, traits that had helped her navigate through the many challenges life had thrown her way. But nothing could have prepared her for the heartbreak she would experience when she was told that her first pregnancy would not result in a happy family she had always dreamed of. Emily's first child was born still, before it had even begun, due to severe heart defects. The doctors explained that her baby had a congenital heart condition so severe that survival had never been an option. The news shattered her, leaving her in a fog of grief and despair. However, Emily was not one to give up easily. After mourning her loss, she resolved to try again, determined to bring a healthy child into the world. Months passed, and eventually, Emily found herself pregnant once more. The early weeks were a blend of hope and fear, as she wrestled with the possibility of another heartbreak. Her anxiety grew as she approached the 21-week mark, the time when a detailed ultrasound would reveal the condition of her baby's heart. The day of the ultrasound arrived, and Emily, her husband, and her mother-in-law all waited nervously as the technician performed a scan. The room was silent as the technician worked, her eyes fixed on the monitor. The tension in the air was palpable. Then, the technician turned to Emily with a look of concern. The technician noticed something unusual and quickly fetched the doctor. The doctor entered the room, looked at the ultrasound images, and then turned to Emily with a serious expression. At this stage, there appears to be a ventricular septal defect of significant size. The doctor explained, while it's too early to fully assess the impact, larger defects like this can sometimes lead to complications. We'll need to monitor this closely, and depending on how things develop, surgery might be necessary after birth. Emily's heart sank. The thought of losing another child, of enduring that pain again, was unbearable. She nodded numbly as the doctor spoke, struggling to find words. Determined not to face another devastating loss, Emily sought alternative treatments. She discovered a doctor who was well-versed in non-traditional therapies, including peptides, a treatment not commonly used or accepted during pregnancy, despite having substantial evidence supporting its safety and benefits. This new doctor recommended a specific peptide protocol, and Emily decided to give it a try. Peptides, often labeled as contraindicated during pregnancy, have shown remarkable benefits in numerous studies. They have demonstrated effectiveness in improving conditions such as preeclampsia, miscarriage, and other pregnancy complications. They've been shown to enhance immunogram and coagulation parameters, reduce childbirth complications, increase spontaneous labor, and decrease labor weakness. Some studies even reported a significant reduction in fetal asphyxia. However, the specific peptides recommended by this new doctor were those showing promise in regenerating myocardial tissue. Emily knew this was far from a guaranteed solution, but she was willing to try anything to save her baby. After consulting with her husband and family, she started the peptide protocol at 21 weeks. The weeks that followed were filled with hope and uncertainty. Emily prayed that the treatments would work and that her baby's heart would heal. She attended regular checkups, each time holding her breath as the doctors examined the progress. For the first few weeks, there was little change, and Emily's heart ached with worry, but she refused to give up hope. Then, at 32 weeks, a miracle happened. During a routine ultrasound, the technician's expression changed from one of concern to surprise. She called the doctor into the room, and together they examined the screen. This is incredible, the doctor said, turning to Emily with a smile. The defect has completely healed. Your baby's heart appears completely normal. Emily couldn't believe what she was hearing. The hole in her baby's heart, which had threatened to end her pregnancy in tragedy, was gone. The doctors were astounded. They had never seen anything like it, but the proof was right in front of their eyes. These peptides, it seemed, had worked a miracle. The remaining weeks of Emily's pregnancy were filled with joy and anticipation. When the day finally arrived, she gave birth to a healthy baby girl. The baby's heart was strong, and she showed no signs of the defect that had once threatened her life. Emily held her daughter close, tears streaming down her face, overwhelmed with gratitude. This is a true testament to the power of peptides and their ability to not only halt the progression of heart damage, but to reverse it entirely. This was not just a temporary fix or band-aid solution, but rather a true cardiac regeneration. It was a breakthrough that promised to change the landscape of cardiology, offering hope where there had been none. If the story were to spread through the medical community and mainstream media, that is. But the truth is almost nobody knows about it. Even if they did, it would go against conventional wisdom, which has long held that regenerating myocardial tissue is extremely difficult and limited. However, just because most people think it's not possible does not mean it isn't. They simply haven't seen the data we have access to. A handful of peptides have proven their ability to regenerate myocardial cells, even those that have died from ischemic reperfusion injuries, such as those caused by heart attacks. This ability isn't limited to just one peptide, nor is it exclusive to unborn children, who have more pluripotent cells and a higher healing capacity. Emily's story only scratches the surface. Imagine reducing your heart rate by 10 to 15 beats per minute and improving your VO2 max if you're an athlete. Consider having fewer angina attacks, reducing pain in your heart region, alleviating weakness, dizziness, headaches, tinnitus, and palpitations. All of these outcomes are within reach thanks to peptides. But how do they work? As the world's leading expert in peptide science, my obsession has been in studying the detailed mechanisms to uncover the secrets behind the power of peptides. They may sound too good to be true, but once you dive into the mechanisms, you'll find that the data supports the outcomes seen in both animal and human trials. Peptides regenerate the heart by multiple mechanisms. First, upregulating actin, a protein involved in cell migration, wound healing, and tissue repair. Tubulin, a microtubule protein, helps maintain cell structure, while vimentin, a filament protein found in fibroblasts, supports tissue integrity. Lamin A and lamin C improve nuclear structural support, help maintain chromatin structure, and repair DNA, which enhances gene accessibility and transcription. When these factors are upregulated simultaneously, myocardial tissue regeneration is significantly improved. Take Sarah, one of our clients, as an example. Using these peptide strategies, we were able to enhance her left ventricular ejection fraction from 40% to 68% in just three months. This remarkable improvement illustrates the transformative potential of peptide therapy in cardiac care. The science behind these peptides is not just theoretical, but backed up by animal and human trials, showing tangible results. The breakthrough peptide treatments are making what once seemed impossible, a reality. Emily's story and Sarah's dramatic recovery showcase just how far we've come in cardiac regeneration, and offer a glimpse into heart health that is possible today with the right knowledge, and is one of the benefits of our molecular bioenhancement coaching. This has been Brenden Henry, the world's leading expert in peptide science, who created the most comprehensive peptide course on the entire planet, covering 69 peptides and backed by over 300 scientific studies. This over three hour video course is neatly organized into sections for healing and optimizing each organ beyond its natural capacity for your age, whether you're looking to improve your health or enhance your performance. It includes quick reference guides, protocols, cheat sheets, and bonus modules showing you how to take your anti-aging and longevity, or physical performance enhancement goals, to the limit with highly synergistic peptide supplement and strategy combinations, so that you can get an advantage over others who have no clue about this information.

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Secrets of Tadalafil

Secrets of Tadalafil

Secrets of Tadalafilbrenden henry
Published on: 09/10/2024

What if I told you that Cialis, a drug known for its use by elderly men to strengthen their erections, is actually one of the most potent health enhancers for men on the planet? Most guys are embarrassed at the thought of even using it, but Tadalafil, as it's officially called, is not just erectile dysfunction medication. Not only does it help with blood flow for erections, but this ED medication can literally prolong stem cell life, which can give your body the ability to regenerate almost any tissue, even if they normally won't heal. For example, one guy had a foot wound that would not heal for 20 years until he started Tadalafil. Tadalafil is useful for improving the function of the heart after an ischaemic injury such as a heart attack, and has been shown to result in a 13% lower incidence of major cardiovascular events, 25% lower mortality, and 39% lower cardiovascular related mortality compared to a control group in patients who had at least one cardiovascular disease risk factor. Tadalafil also enhances muscle growth and enhances bone strength through its ability to increase testosterone and upregulate androgen receptors. Tadalafil helps to reduce symptoms of benign prostatic hyperplasia by improving the testosterone to estrogen ratio, relaxing smooth muscle in the prostate and bladder, and improving blood flow, which can reduce symptoms like frequent urination and slow urination. Tadalafil can reduce blood pressure and improve endothelial function, thus lowering the risk of cardiovascular disease through regulating endogenous antioxidant production and dilating arteries, which can help prevent a blood clot from forming. Many people take aspirin to help prevent blood clots, and this works by thinning the blood, but the downside to this is that it can increase brain bleeds from trauma. Tadalafil doesn't thin the blood, it just dilates arteries, which could potentially make it a safer option, but it can still cause side effects if you use it incorrectly. So by the end of this video you will learn how to use Tadalafil most effectively, and an incredibly powerful synergistic combination you can use with it to get more healing power. My name is Brenden Henry, the world's leading expert in peptide science. I was the first person to make a video on the incredible power of the vesugen peptide for enhancing the proliferation and differentiation of mesenchymal stem cells and delaying their senescence. This is huge because stem cells cost tens of thousands of dollars, but this peptide can increase your own naturally for a small fraction of the price of stem cell clinics. This can lead to the acceleration of healing in your body. Whether you have an organ that's damaged, a joint, muscle, or recently undergone a surgical procedure, this will help you heal more quickly. And you can get even more benefits out of it by combining it with Tadalafil. This protocol can work well on its own, or it can be used to enhance the effects of stem cells you receive at the clinic. I currently have a client who purchased my peptide mastery course and coaching, link in the description, and he is looking to maximize the potential of a stem cell treatment at the clinic. So this is of course one of the things included in our protocol, and just one example of how traditional medications or supplements can synergize with certain peptides in ways that are not known by the majority of the people on the planet. In this video, I want to talk about what Tadalafil is and how it works on a mechanistic level so that you can understand the benefits it has to offer more clearly and be more willing to confidently use it to enhance yourself. Then I will tell you how to best use it and dose it so that you get all of the benefits without any toxic effects. First, Tadalafil is a PDE5 inhibitor that prevents the breakdown of CGMP, which enhances blood flow by promoting vasodilation. While it doesn't create CGMP directly, which requires nitric oxide, it helps increase CGMP levels by stopping its degradation. However, PDE5 inhibitors have some crosstalk with PDE8, which are high affinity C-AMP specific enzymes, leading to increased nitric oxide production indirectly. This crosstalk is significant because without it, these inhibitors would be much less effective because they'd have less nitric oxide to work with. Tadalafil's attributes extend to stimulating endogenous antioxidant production in muscle cells, cavernous tissue, and lung endothelial cells. This effect is due to hormesis, which is the body's upregulated production of endogenous antioxidants in response to a mild stressor, leading to a net protective effect. Evidence of this is seen in lung endothelial cells, where Tadalafil, by activating the CGMP-PKG1 pathway, enhances cellular antioxidant defenses, protecting against oxidative stress and dose damage. This leads to improved endothelial function in humans. Tadalafil also reduces the risk of thromboembolism, which is blood clots in males. Getting further into the mechanistic data, PDE5 inhibition increases CGMP levels, which stimulates PKG1 and also leads to an increase in androgens. PKG1 and PKG2 mediate the effects of CGMP, and Leydig cells express mRNA for both. However, inhibiting PKG leads to a dose-dependent decrease in androgen production, indicating that PKG is necessary for the CGMP-driven rise in androgens. When Tadalafil activates CGMP-PKG1, it phosphorylates the star protein, enhancing the transport of cholesterol into mitochondria and increasing testosterone production in Leydig cells. PDE5 inhibitors also interact with PDE8, leading to an intracellular C-AMP increase in Leydig cells, further facilitating testosterone production. Mice with PDE8 knockout have up to 4x more testosterone. Tadalafil has been shown to increase testosterone levels by an impressive 40% in men with metabolic syndrome over time. In a direct comparison with Sildenafil, Tadalafil has been found to be superior at increasing testosterone. Tadalafil can also enhance the testosterone-to-estrogen ratio by inhibiting the aromatase enzyme, and it increases androgen receptor density while improving lean body mass. It has been shown in human studies that you can expect to gain a couple pounds of lean mass and lose a couple pounds of fat from long-term Tadalafil use. Tadalafil improves bone strength and wound healing. It increases androgen receptors and decreases aromatase in osteoblast cell lines and was able to enhance fracture healing in a rat femur and improve bone density. Tadalafil also improves burn wound healing. Moving up to the brain, in elderly patients with erectile dysfunction, Tadalafil improves cerebral blood flow in the postcentral gyrus, precuneus, and brainstem, and enhances cognitive function, as assessed by the Montreal Cognitive Assessment Score. While it's uncertain if this effect occurs in younger men, Tadalafil has enhanced working memory in both young and old mice. Now let's get into how you should dose Tadalafil for maximum benefits and low side effects, even though its safety is well established. If you dose it too high, you may get occasional headaches, flushing, a stuffy nose, but there are two even worse side effects than that. One, muscle pain. Two, aortic damage and testicular toxicity. The muscle pain can occur because Tadalafil is a slight off target for PDE11 inhibition, which is known to cause muscle pain, especially back pain. At 5mg, this effect of Tadalafil is barely relevant, but it becomes more relevant once you go up to 10mg+. The aortic damage can occur due to oxidative stress combined with too much dilation. You see, Tadalafil is a hormetic stressor, as mentioned earlier, and this is how it increases endogenous antioxidant production, and is consistently shown to be net protective at 5mg human dosages. It's protective to the testes at these doses, as well, in both humans and mice who received an equivalent dose converted for their species. However, if you look at rodent studies, you will see that at a 20mg equivalent dose, that changes, and starts to have a net toxic effect. MDA levels increase, which are markers of oxidative stress, and antioxidant levels drop. The same case would be true if you did HBOT for 15 hours a week, which is hyperbaric oxygen chamber therapy. Some is great, but once you cross a certain threshold, it becomes toxic. This also relates to how some people using Tadalafil mention a slight dip in sex drive over time. This can occur if they are taking too high of a dose, usually 10mg+, and it can happen for a couple reasons. The first, is that it can start to induce oxidative stress in some people, as mentioned. And the second, is that it can reduce estrogen levels with long-term use, and estrogen is important for libido. This is why you need to use no more than 5mg a day, and also monitor your blood work for your testosterone to estrogen ratio. But you need to request LC-MS, MS, because this is the only accurate way to measure hormone levels. Doctors are mostly just concerned if something is within range, not if it's optimal. If your estradiol levels are near the low end of the range, and your testosterone levels are mid-range or high range, then you may consider adding in something to raise your estradiol up. DHEA or Omnibol, which contains pregnenolone and DHEA, is great for this, and Boron can help some people to a lesser extent, and also raise free testosterone slightly. In conclusion, Tadalafil is a fascinating and underappreciated compound with uses in healing broken bones, chronic wounds, heart damage, and increasing testosterone levels. For the best results, for both blood flow and stem cells, consider combining it with Vesugen, a tripeptide with a sequence lys-glu asked. To learn more, get the peptide mastery free edition on my website, linked in the description. You can also get our free guide, Toxic Testosterone, which reveals the hidden dangers of the 5 most commonly recommended testosterone supplements, and what to do instead. This has been Brenden Henry, the world's leading expert in peptide science.

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The Future of Human Healing - Vesugen (The Stem Cell Activation Peptide)

The Future of Human Healing - Vesugen (The Stem Cell Activation Peptide)

The Future of Human Healing - Vesugen (The Stem Cell Activation Peptide)brenden henry
Published on: 22/06/2024

Stem cells give your body the ability to regenerate almost any tissue or organ, can reverse aging, and can heal your brain and body as if you have a superpower. But stem cell therapy ranges from $5,000 to $50,000. What if I told you there's a peptide

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